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Should I consider an SGLT2 inhibitor instead of or in addition to a GLP-1 medication, especially if I have heart failure or kidney disease

You might need a BMI above a certain threshold, a related health condition (like high blood pressure or sleep apnea), or a prior authorization from your provider

Whether this should be regarded as specific metabolic treatment, targeting only the metabolic alterations of the syndrome, is debatable, since the improvement in metabolic conditions, e.g., insulin resistance, would tenably have a positive impact also in gonadal function in women with PCOS

As it interacts with NO to form S-nitrosoglutathione (GSNO), it stabilizes NO so it is released slowly