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This long-lasting feeling of fullness can reduce temptation to overeat and improve the negative associations many overweight individuals have with a reduced-calorie diet
Wuttke, W., Jarry, H., Haunschild, J., Stecher, G., Schuh, M., & Seidlova-Wuttke, D
Sattar, D
In addition to its extensively studied actions in peripheral tissues, studies have evaluated the distribution of GLP-1R in the central nervous system (CNS) of rodents, non-human primates, and humans, showing that it is widely diffused to multiple CNS neurons including neurons of the arcuate nucleus (ARC), which are crucial for the control of energy balance (Fig
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