While there is evidence of a reduction in cardiovascular risk in diabetic patients treated with semaglutide, the long-term effects in subjects with other comorbidities must be clarified
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Certain patient populations or medical conditions may be more susceptible to experiencing adverse reactions when using the medication off-label
Effect of synthetic peptides on aging of patients with chronic polymorbidity and organic brain syndrome of the central nervous system in remission
In recent years, the therapeutic footprint of this class has grown: long-acting agents (e.g., liraglutide, semaglutide) and next-generation dual/triple agonists (e.g., tirzepatide) have demonstrated superior glycemic control, weight reduction, and cardiovascular benefits in adults with T2DM (Yao et al., 2024)