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doi: 10.1038/s41467-018-05451-7 98 FranznAHeldinNE

Thromboembolism events reported in postmenopausal women with operable breast cancer who received adjuvant tamoxifen therapy (n = 3094) in the ATAC trial venous thromboembolic events (5%), DVT (2%), and ischemic cerebrovascular event (3%)

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This makes it one of the more common side effects, occurring at similar rates to nausea and diarrhea

In a trial in participants with non-alcoholic fatty liver disease, a condition strongly linked to insulin resistance, treatment with gynostemma extract, as an adjunct to diet, resulted in a significant reduction in liver enzymes and insulin levels, a decrease in body mass index, and increased insulin sensitivity (Chou 2006