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Clinical efficacy studies of various unimolecular dual and triple agonists targeting the GLP- 1 receptor, GIP receptor, and glucagon receptor have shown promising results when used alone or in conjunction with approved hypoglycemic medications

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What lipotropic injections plausibly contribute is more modest and more defensible: correction of real deficiencies, a tolerable non-stimulant option for patients who cannot or will not take prescription weight loss medication, and a recurring touchpoint that keeps patients engaged with a supervised program

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High tolerance makes drinking more costly in terms of calories and money, limits the euphoria, and worsens the depressant effects