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Tirzepatide, the active ingredient in Zepbound and Mounjaro, targets both GLP-1 and a second receptor called GIP (the gastric inhibitory peptide receptor), which boosts the effects of the GLP-1 by improving metabolism and reducing nausea-related side effects

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Week-by-week expectations when escalating to 50 units If your provider has prescribed a dose that works out to 50 units on your syringe, knowing what to expect during the escalation helps you stay on track and recognize whether your experience is normal

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Cell 31 , 722733 (2014)

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Long-term inhibition of dipeptidyl peptidase IV improves glucose tolerance and preserves islet function in mice

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