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Xie, N., Zhang, L., Gao, W., Huang, C., Huber, P.E., Zhou, X., Li, C., Shen, G., Zou, Bingwen, NAD+ metabolism: pathophysiologic mechanisms and therapeutic potential, Signal Transduction and Targeted Therapy

Serious drops in either or both is a sign that the drugs are causing an increased effect, and you may need to adjust your dosages

Patients who have microdosed GLP-1 medications have reported an easier adjustment period, with minimal GI side effects, and a reduction in intrusive thoughts, cravings, and focus on food (often called food noise), even at sub-therapeutic doses

In obese or diabetic individuals, this can be an issue

Intrinsic factor binds to B12