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Underscoring the potential health consequences from dosing errors and exposure to the wrong ingredients, in September 2025, the FDA reported receiving 1,150 reports of adverse events associated with compounded GLP-1 drugs, including hospitalizations and some deaths

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While our recent report has shown that over 7% of all prescriptions are for GLP-1-based therapies ( 8 ), oral formulations may lower barriers to initiation by offering a non-injectable option that can be prescribed and managed in a broader range of clinical settings