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The mechanism difference that matters Semaglutide is a single-agonist it mimics GLP-1 (glucagon-like peptide-1)
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Crucially, several of these effects appear independent of weight loss, strengthening the argument that GLP-1s promote direct neurobiological benefits for brain health and dementia prevention
Mood changes: Some individuals experience irritability, anxiety, or emotional ups and downs, particularly as the medication wears off
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