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Scenario 2: Inadvertent Exposure 32-year-old woman with T2DM on semaglutide, presents at 8 weeks gestation G2P0L0A1.First trimester pregnancy loss due to high blood glucose levels Management- Stop Sema Reassurance based on current evidence Detailed risk counseling using available data HbA1C specially Enhanced monitoring with detailed ultrasound Multidisciplinary approach Documentation and registry participation if available What Guidelines Say
Lipids 1862 , 666675 (2017)
However, the study had no control group and several methodological issues, so the results should be viewed with caution
It means the peptide remains bioactive and available to cell receptors for a much, much longer period
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