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Models explore pulsatile GH-axis dynamics, second-messenger responses, and combinatorial pathway effects in vitro
C.PengC
Novel uses in unconventional areas such as neurodegenerative conditions, non-alcoholic steatohepatitis (NASH), and cardiovascular disease prevention may enhance the therapeutic potential of these medicines
Effective pharmacological treatment for obesity exists
In addition, it has been demonstrated the specific involvement of endothelial GLP-1R in contributing to the anti-hypertensive effects by controlling nitric oxide bioavailability (Richards et al., 2014
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