(As a side note, I was intrigued that the control group had lower medical costs than the GLP-1 users, and materially lower medical + Rx costs, at the end of the second year regardless of the higher trend.) That total cost picture aligns more closely with my expectations and experience, but differs a lot from the headline message
For instance, in the SUSTAIN-6 trial, semaglutide was associated with a significantly higher ratio of retinopathy complications compared with placebo, including vitreous hemorrhage, retinal photocoagulation, and intravitreal therapy
Researchers believe GLP-1 receptor agonists may also affect stress pathways linked to relapse
The two products of the non-oxidative phase are then converted to glucose 6-phosphate through a process known as gluconeogenesis
5-Amino-1MQ has limited research data