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The effectiveness of GLP-1 agonists can vary based on individual factors, making personalized treatment plans crucial for success

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Why GLP-1s Cause Cold Sensitivity Many people taking GLP-1 receptor agonists such as semaglutide (Ozempic, Wegovy) or liraglutide (Victoza, Saxenda) report feeling persistently cold, though this is not listed as an official adverse effect

Oxidative stress is closely related to the occurrence of GC, and antioxidants have inhibitory effects on GC 52,53