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Nimesulide (219), Vismodegib (220), New Pyrimidine-5-Carbonitriles (221), Sulfonamide-Pyrazole derivatives (222) and lariciresinol (223) exert regulatory effects on arachidonic acid metabolism by inhibiting COX-2, the specific drugs used are shown in Table 5
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Glutathione defense mechanism in liver injury: insights from animal models
The remarkable commercial success of drugs like semaglutide and tirzepatide has created strong market momentum, driving significant investment in next-generation molecules and accelerating development cycles
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