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248 GLP-1 can effectively bind to receptors on -cells, stimulating the secretion of somatostatin
they cannot establish incidence, causation, or safe use
Some insurance plans have started covering Wegovy more widely, particularly after it gained FDA approval to reduce cardiovascular risk
Although SGLT-2 inhibitors and GLP-1 receptor agonists do not increase the risk of severe hypoglycemia, SGLT-2 inhibitors increase the risk of genital infections, and GLP-1 agonists have gastrointestinal adverse effects, especially at initiation and with high doses
These findings are consistent with data accessed on April 24, 2025
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