Reductions in alcohol and substance use GLP-1 medications were associated with decreased alcohol consumption and reduced substance use in several studies from this 2024 review
Tanaka S, Hikita H, Tatsumi T, Sakamori R, Nozaki Y, Sakane S, Shiode Y, Nakabori T, Saito Y, Hiramatsu N, Tabata K, Kawabata T, Hamasaki M, Eguchi H, Nagano H, Yoshimori T, Takehara T
Safety and efficacy of tirzepatide as an add-on to single oral antihyperglycaemic medication in patients with type 2 diabetes in Japan (SURPASS J-combo): A multicentre, randomised, open-label, parallel-group, phase 3 trial
A total of 33 proteins (including N-terminal pro B-type natriuretic peptide (NT-proBNP)) were significantly regulated in STEP 1 but not in STEP 2, although this may be owing to the larger sample size in STEP 1 than in STEP 2
D.RopoloA.et al (2017)