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Its clinical translation will require formal validation in human studies and the development of advanced delivery systems to overcome restrictions in bioavailability
Int J Biol Macromol
Conversely, defective ALP exacerbates mitochondrial dysfunction and protein aggregation, creating a feed-forward loop that amplifies ROS levels and cytotoxicity (Tang et al., 2025)
It has also been observed that patients taking GLP-1 or GLP/GIP medications are at risk of losing lean muscle mass during weight loss, so it is important for patients to maintain adequate sources of protein in their diets
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