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Germ-free mice orally administered with IBD patient saliva containing Klebsiella aeromobilis developed colitis by inducing the accumulation of intestinal T helper 1 cells, while the inflammatory state in IBD may render the intestine more permissive to aerotolerant oral-derived bacteria than the steady-state intestine (Atarashi et al., 2017)

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This built-in budget validation ensures that procurement stays within the companys financial limits