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Patients losing substantial weight should have their dosing reviewed if they approach this threshold, particularly if they also meet one of the other criteria (age 80 years or serum creatinine 133 micromol/L)

follow the conservative 28-day window if uncertain Store in box or opaque container to block light Place on back shelf, not door Never freeze the reconstituted vial Inspect the solution before every dose

10 While the metabolic advantages of GLP-1RAs likely explain some of these positive findings, other mechanistic possibilities include immunoregulative functions

Causal Inference : What If (CRC Press, 2010)

2022 Oct 28;10(11):2744