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TF3 causes cell death in the OVCAR-3 cell line, which was derived from ovarian cancer (Gao et al., 2019)

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As a consequence, although clinical application of PAC may be considered as safe, in the case of severely depleted GSH levels PAC should be administered with caution, especially in subjects with severe GSH depletion who, again, are those at higher risk of developing severe COVID-19 disease

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