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Comparing the glutathione-scaffold site among a variety of other members of the thioredoxin superfamily also provides an explanation for their disulfide substrate preferences, for example, why glutaredoxins prefer GSSR in contrast to thioredoxins lacking most of the relevant residues (Fig
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Frias JP, Nauck MA, Van J, Kutner ME, Cui X, Benson C, et al
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Interestingly, nanoparticle (NP)-induced cell death has been described recently as being consistent with the new 5 R principle
