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Over-the-counter sleep supplements like melatonin, valerian, magnesium, and L-theanine provide compounds that support sleep through various mechanisms

By activating all three receptors, Retatrutide aims to deliver superior appetite suppression, improved insulin sensitivity, and enhanced energy metabolism, which may lead to more substantial and sustained weight loss compared to single-pathway therapies

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As research continues to evolve, healthcare providers can help patients understand current evidence, limitations, and appropriate clinical considerations