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Development and testing of advanced delivery strategies, such as nanoformulations and prodrugs, are needed to overcome bioavailability challenges and improve central nervous system penetration and target engagement
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doi: 10.1210/clinem/dgz096 54 QuarellaMWalserDBrndleMFournierJYBilzS
Additionally, it is important to note that the available RCTs have utilized a plethora of cognitive tests to study the effects of micronutrient supplementation
Drug interactions A number of cholesterol-lowering medications (like cholestyramine and colestipol), as well as orlistat, sucralfate, mineral oil, and the fat substitute olestra, which interfere with fat absorption, may theoretically decrease the absorption of fat-soluble vitamins, including vitamin E
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