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If you have an MTHFR polymorphism, enzymatic reactions can slow down by 40-70%
These are associations rather than proof that altering NNMT activity reverses metabolic changes, but they motivate continued research into NNMT inhibitors in metabolic models
It has a 50-plus-year research history spanning skin repair, wound healing, collagen synthesis, anti-inflammatory activity, and some hair-related findings
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