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Although todays semaglutide market is largely OOP, falling costs could tip the scales for wider public reimbursement where insurers may be more willing to cover AOMs, in addition to simplifying coverage by removing restrictions such as prior authorisation (see section above on public reimbursement)

Lost ~18-22% of body weight

Metabolic Pathways and Half-Life Tirzepatide is primarily degraded by proteolytic enzymes and exhibits a half-life of approximately five days, enabling once-weekly dosing

BioRxiv 235721 [Preprint]

As a result, retailers should prepare for an influx of shoppers, especially women, looking to find clothes that are a better fit