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Serum C22 lactone sulfate, a molecule strongly linked to the modulation of androgenic steroid metabolites, was found to be substantially reduced by a high-dose of vitamin E (400 IU/day) (151)

VEGF also regulates and shapes immunosuppressive TME by inhibiting dendritic cell maturation, preventing antigen presentation, and by polarizing macrophages toward an M2 phenotype

These studies are usually short, often funded by the formulator, and almost always test multi-ingredient products rather than GHK-Cu in isolation

doi: 10.1007/978-3-319-15126-7_3 36 LambertIHKristensenDMHolmJBMortensenOH

The study was focused on cardiovascular outcomes like heart attack and stroke and cancer, and it found no benefit from vitamin D compared to placebo, Bent said