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GLP-1 receptor expression in endothelial cells, vascular smooth muscle cells, macrophages, and monocytes suggests a potential anti-atherosclerotic effect of GLP-1 RAs [49,50,51]
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Tirzepatide is administered as a once-weekly subcutaneous injection, with dosing typically initiated at 2.5 mg for 4 weeks, then increased in 2.5 mg increments to a target dose of 5-15 mg based on glycemic control and tolerability
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