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Nanoprobe-based GSH imaging relies on signal-generating reactions triggered by glutathione, and effective tumor visualization requires that these signals clearly differentiate malignant tissue from normal tissue

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By comparing the growth of D39 and SPD1296 deletion mutant (SPD1296) with no or 200 g/mL methionine, we observed that deletion of SPD1296 impaired bacterial growth severely when no methionine was supplied (Figure 4D)