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This overlap makes it challenging to distinguish medication side effects from disease activity and raises questions about tolerability in this patient population
The combination addresses multiple systems simultaneously
It belongs to a class of next-generation research peptides studied for their ability to modulate several metabolic signaling pathways at once, rather than targeting a single receptor in isolation
Electrical stimulation of the OB induces electrophysiological responses in the LH and the PVN 36,37 , many of the structures to which the OB projects via the MCs, such as the AON, the olfactory tubercle and the piriform cortex, also project to the LH 37,38,39
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