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Research shows rapid weight regain, appetite dysregulation, and metabolic rebound within weeks of cold-turkey cessation, making supervised tapering the evidence-based approach

Available as both a weight loss injection and an oral pill, semaglutide mimics the natural GLP-1 hormone, effectively curbing appetite to support substantial and long-term weight loss

Metformin, common for diabetes, can nudge the scale down modestly

doi: 10.2337/dc12-2006 77 RosenstockJRaccahDKornyiLMaffeiLBokaGMiossecPet al

For the treatment of adults with insufficiently controlled type 2 diabetes mellitus as an adjunct to diet and exercise: as monotherapy when metformin is considered inappropriate due to intolerance or contraindications in addition to other medicinal products for the treatment of diabetes