muscle weakness semaglutide impacts skeletal to a similar extent as caloric restriction in mice with diet‐induced obesity - Jeromson - The Journal of Physiology Does Semaglutide Cause Muscle Loss?

This is a crucial question for individuals prescribed glucagon-like peptide-1 (GLP-1) receptor agonists such as semaglutide (Ozempic, Wegovy) or liraglutide (Victoza, Saxenda) in the UK

Get your heart checked

Interestingly, in a study published in 2024, researchers examined the dynamic, wide-ranging molecular environment in the intact human ileum and found that when plant-based foods with intact cellular structures are consumed, they can increase the delivery of nutrients to the ileum, which subsequently can lead to an increased release of satiety peptides (in particular, PYY)

As we await prospective data, clinical practice should consider the difference between abrupt stop vs gradual taper when counseling patients about expectations after therapy

Avoid higher doses because you run the risk of greater side effects without any proven benefits