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doi: 10.1590/1806-9282.65.8.1094 38 SeibtT
5): (1) reduction of CoQ10 through the Nrf2-FSP1 axis to inhibit the generation of lipid peroxides, thereby mitigating the occurrence of cellular ferroptosis
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In this regards, we have shown earlier that reducing conditions favor activation of primary human T-cells (15), whereas oxidative stress leads to hyporesponsiveness or even cell death of primary human T-cells (16, 17)
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