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But again, the message is this is not elimination but a reshaping of their engagement with the baked goods category. The Playbook survey revealed that an equal percentage of GLP-1 users (36%) either decreased or increased their consumption of baked treats since starting on the medication, with the rest reporting their intake of baked treats has stayed the same
Although not powered to do so, a phase 2 study also found favorable effects of resmetirom on liver histology, and the drug has an encouraging cardiovascular profile, with reduced serum lipids, including LDL cholesterol
But it can also lead to nausea in addition to other side effects, such as vomiting, bloating, and abdominal pain
A commonly referenced protocol ramps from 1 mg daily for 15 days to 2 mg daily for days 16 to 30, injected subcutaneously before bed, followed by a 30-day rest period before the next cycle