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A high prevalence of insulin resistance was identified in a sample of 154 non-diabetic PD patients, with 58% being insulin-resistant as indicated by abnormal Homeostatic Model Assessment for Insulin Resistance (HOMA-IR) scores [157]

First, it would appear that gut dysbiosis is a cause and consequence of CNS pathology and hence creates self-propelling loops among inflammation, immune activation, and barrier dysfunction

doi:10.3390/medicina59040778

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