Many commercial products have been approved for scaffold-associated chondrocyte implantation for more than a decade in Europe and Australia, such as Chondro-Gide (a bilayer collagen type 1/3 scaffold, manufactured by Geistlich Biomaterials, Wolhusen, Switzerland), Hyaff-11 (a hyaluronan-based scaffold, manufactured by Fida Advanced Biopolymers, Abano Terme, Italy), and BioSeed-C (a synthetic polymer scaffold composed of fibrin, polyglycolic/polylactic acid, and polydioxanone, manufactured by BioTissue, Zrich, Switzerland)
Co-pays: Half of covered patients have a co-pay of $50/mo or less
doi: 10.1089/derm.2023.0360 165 KurzBArndtSUngerPIvanovaIBerneburgMHellerbrandCet al
Baklund IH, Dammen T, Moum T, Kristiansen W, Duarte DS, Castro-Marrero J, et al
By month four, the vast majority of patients report energy levels equal to or better than baseline