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As of June 2025, all compounding of semaglutide and tirzepatide, except in rare circumstances, is now illegal under U.S

10.1016/j.bbrc.2016.05.106 120 ZhangY.HuangS.LiP.ChenQ.LiY.ZhouY.et al (2018)

Some patients explore peptide therapy for wellness goals related to recovery, energy, and healthy aging support

We need to focus more time and energy in developing GLP-1s in an oral form to make this [treatment] more sustainable, because there is a crisis in supply and demand with the injectables, Reierson said