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Adipocyte inflammation is the primary driver of hepatic insulin resistance in a human iPSC-based microphysiological system
Its interaction with multiple melanocortin receptors supports investigations into neuroendocrine signalling, receptor selectivity, and peptide structure-function relationships under controlled experimental conditions
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The researchers also examined the effects of liraglutide (Saxenda and Victoza), a GLP-1 prescribed for weight loss and type 2 diabetes, and found a 28% lower risk of alcohol-related hospitalization among subjects
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