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Possible Direct Mechanisms Although indirect effects dominate, GLP-1 receptors are expressed in reproductive tissues, suggesting potential direct roles: Ovarian Effects: Animal studies demonstrate GLP-1 receptor activation can influence granulosa cell function, increase cyclic adenosine monophosphate (cAMP), and modulate steroidogenesis
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t.v., transvenous
References Canadian Agency for Drugs and Technologies in Health (CADTH)
Common adverse effects include gastrointestinal symptoms such as nausea, diarrhea, vomiting, and constipation, which typically diminish over time
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