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The most common side effects reported in the tirzepatide groups were diarrhea and nausea.In patients with type 2 diabetes who had inadequate control of blood sugar levels despite treatment with insulin glargine, adding subcutaneous tirzepatide to titrated insulin glargine led to significant improvements in glycemic control after 40 weeks, along with reductions in body weight

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The composite primary outcome was achieved with one of the following: a 40% reduction in eGFR, kidney failure or death due to kidney disease