Source: Hwang, et al JAMA Health Forum March 14, 2025 Researchers from the University of Chicago modeled the clinical and financial impact of anti-obesity medications: Zepbound (tirzepatide), Wegovy (semaglutide), and two oral generic drug combinations, phentermine-topiramate and naltrexone-bupropion
Enhances Hydration: Dry, dehydrated skin can lead to premature aging and a dull complexion
Heres whats coming soon, and whats in clinical trials: Orforglipron (brand name Foundayo): A once-daily oral GLP-1 was just approved by the FDA for weight loss, and will hopefully be approved for type 2 diabetes soon
Combining medication with behavior change is powerful because the patient is more likely to experience early success, leading to a greater likelihood to stick with the program and transform a new habit into permanent lifestyle change
This caution is based on findings from animal studies and limited human case reports