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Taking advantage of the reversibility of Michael addition reaction, we developed the first reversible reaction-based fluorescent probe ThiolQuant Green to perform single-point quantification of GSH in living cells 15

387 Indeed, most small molecules drain primarily from interstitial spaces through blood capillaries, given that blood flow rates are 100 to 500 times faster than lymphatic flow rates, constraining drug delivery

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Furthermore, the impact of endothelial cell senescence is not limited to the vascular system

"Obviously, we have the expansive platform, whether it's the oral medications that are already out there or if there is some reason that this patient would qualify for some level of personalization that exists