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B12 shots are usually given into a muscle, like your upper arm or thigh

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Larger total quantities would shift the cost-per-mg slightly but at the trade-off of needing to consume larger reconstituted volumes within the window

Dosing & Reconstitution Guide Educational guide for reconstitution and daily dosing Standard FDA-Approved Protocol (3.0 mL = ~3.33 mg/mL) Frequency: Inject once daily subcutaneously, preferably in the evening to coincide with nocturnal GH release [5] [6]

Hydroxocobalamin lasts longer, possibly needing less frequent doses