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DPP-4 inhibitors: Focus on safety
Initial therapy with the combination of Januvia and metformin provided significant improvements in A1C, FPG, and 2-hour PPG compared to placebo, to metformin alone, and to Januvia alone (Table 5, Figure 1)
There have been instances of kidney problems showing up in people experiencing significant nausea, vomiting, or diarrhea conditions that can lead to dehydration and negatively impact kidney function
2 Pregabalin should be initiated at a dosage of 75 mg twice daily and titrated up to a target of 225 mg twice daily, depending on the patients creatinine clearance
Theres evidence that certain foods or certain ways of eating may lower it, but this is really theoretical right now
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