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Participants ate roughly 24% fewer total daily calories than on placeboabout 726 calories less per day
The effect of these peptides is real but modest
Part of that reflects intensifying competition from Eli Lilly, which now commands 58% of total U.S
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On November 6, 2025, the Trump administration announced new pricing and coverage agreements with Eli Lilly and Novo Nordisk for widely used glucagon-like peptide-1 (GLP-1) receptor agonists, including tirzepatide (Mounjaro, Zepbound) and semaglutide (Ozempic, Wegovy)
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