The most common adverse events (ADE) are gastrointestinal issues, and the risks of pancreatitis, kidney failure, and medullary thyroid carcinoma cannot be ignored (Smits and Van Raalte, 2021)
This was the first medicine of its type to get approval for the treatment of type-2 diabetes
Injection site reactions are common but usually mild
Safety advice Check with a clinician before use if you are pregnant or breastfeeding, have diabetes or frequent low blood sugar, have a bleeding disorder, or have liver or kidney disease
Multiple large-scale studies, including a comprehensive meta-analysis published in Clinical Gastroenterology and Hepatology, have definitively shown that low-volume, split-dose preparations are superior to high-volume, single-dose regimens [5,6]