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In TRIUMPH-1, treatment discontinuations due to adverse events occurred at 4.1%, 6.9%, and 11.3% on the 4 mg, 9 mg, and 12 mg arms respectively, compared with 4.9% on placebo [2]
Maintenance and discontinuation: Long-term support is essential, as biological and environmental pressures favor weight regain
For some, this causes grief and sadness, particularly if they had hoped to have more children
No large-scale randomised controlled trials have directly examined probiotic efficacy in this specific population , though related research provides some context
Grzam A et al
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