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Moreover, TB-500 also appeared to have promoted the expression of CD31, -smooth muscle actin (-SMA), Ang2, tie2, VEGFA, N1ICD, and p-p65 in the muscle tissues of murine CLI models

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The five-year incidence of progression to osteoarthritis and total joint arthroplasty in patients prescribed glucagon-like peptide 1 receptor agonists

Western blot analysis Western blot analyses were performed on proteins extracted from skeletal muscle tissue and performed as previously described [23] (see Supplementary Table 3 for antibodies used and more details)