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While not a complete list of warnings and adverse reactions, the most common side effects of GLP-1 drugs generally include: Nausea and/or vomiting, which most often occur after starting the medication and typically ease with time Diarrhea Abdominal discomfort, which may be accompanied by bloating or cramping
75 In view of this, GLP-1RAs have been investigated with the expectation of improvements in both cardiac and renal function in patients with CKD and HFpEF
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