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Clinical trials on NAC in IPF have yielded mixed results: some showed slowed lung function decline [155], while a large phase 3 trial found no significant benefit in preserving forced vital capacity (FVC) in patients with mild-to-moderate IPF [156]

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Preclinical models report accelerated structural restoration following peptide exposure, characterized by increased fibroblast proliferation, enhanced extracellular matrix organization, and improved collagen deposition

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