Diabetologia 57, 13201324
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Vitamin B12 is associated with lowering the levels of homocysteine, an amino acid that is associated with cardiovascular disease
GLP-1 RAs exert direct and indirect effects on the CV system including vasodilation, natriuresis anti-atherosclerotic effects, improvements in endothelial function, anti-inflammatory effects (decrease cytokines level such as tumor necrosis factor, interlukin-1, interlukin-6) and a consequent decrease in C-reactive protein, and reductions in infarct size ( Figure 2 Recently, GLP-1 RAs have been recommended by different guidelines